Oral Signs of Systemic Disease by Unknown

Author:Unknown
Language: eng
Format: epub
ISBN: 9783030108632
Publisher: Springer International Publishing

Clinical Manifestations

Oral presentation of LABD involves painful vesicles, bullae, and erosions that could lead to scarring.

Oral Signs and Symptoms

Ordinarily, oral symptoms of LABD are minor compared to cutaneous symptoms. However, exclusively oral LABD has been reported in the literature. LABD can involve any oral site, as well as extra-oral mucosal sites including the nose, conjunctiva, and genitalia. The principal oral symptoms of LABD are painful vesicles and bullae that progress to ulcerations and erosions with resultant scarring that can be extensive (Figs. 7.12 and 7.13). Generalized DG, gingival hyperplasia, and erosive cheilitis are also clinical features observed in oral LABD. Cutaneous symptoms are valuable in establishing a diagnosis, including extensor surface distribution, clusters of discrete bullae termed as the “jewel sign,” and vesicles or bullae at the border of annular lesions known as “string of pearls.” Unlike the oral mucosa, cutaneous lesions heal without scarring. Depending on the cause, LABD may be chronic, with acute exacerbations and very few cases of spontaneous remission. Removal of an offending medication may lead to complete resolution of LABD.

Fig. 7.12Linear IgA bullous dermatosis. Annular vesiculobulla on the lip

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